The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients

Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC). The VGSC consists of four domains of pore-forming α-subunits and two...

Descripción completa

Detalles Bibliográficos
Autores principales: Sheilabi, Mariam A., Takeshita, Louise Y., Sims, Edward J., Falciani, Francesco, Princivalle, Alessandra P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216270/
https://www.ncbi.nlm.nih.gov/pubmed/32331418
http://dx.doi.org/10.3390/ijms21082955

Ejemplares similares

Ejemplares similares