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Cathepsin S: investigating an old player in lung disease pathogenesis, comorbidities, and potential therapeutics
Dysregulated expression and activity of cathepsin S (CTSS), a lysosomal protease and a member of the cysteine cathepsin protease family, is linked to the pathogenesis of multiple diseases, including a number of conditions affecting the lungs. Extracellular CTSS has potent elastase activity and by pr...
Autores principales: | Brown, Ryan, Nath, Sridesh, Lora, Alnardo, Samaha, Ghassan, Elgamal, Ziyad, Kaiser, Ryan, Taggart, Clifford, Weldon, Sinéad, Geraghty, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216426/ https://www.ncbi.nlm.nih.gov/pubmed/32398133 http://dx.doi.org/10.1186/s12931-020-01381-5 |
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