Ghrelin, a novel therapy, corrects cytokine and NF-κB-AKT-MAPK network and mitigates intestinal injury induced by combined radiation and skin-wound trauma

BACKGROUND: Compared to radiation injury alone (RI), radiation injury combined wound (CI) further enhances acute radiation syndrome and subsequently mortality. We previously reported that therapy with Ghrelin, the 28-amino-acid-peptide secreted from the stomach, significantly increased 30-day surviv...

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Detalles Bibliográficos
Autores principales: Kiang, Juliann G., Smith, Joan T., Cannon, Georgetta, Anderson, Marsha N., Ho, Connie, Zhai, Min, Cui, Wanchang, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216502/
https://www.ncbi.nlm.nih.gov/pubmed/32426105
http://dx.doi.org/10.1186/s13578-020-00425-z

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