Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice

BACKGROUND: Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, and irritability occur in prodromal phases of clinical Alzheimer’s disease (AD), which might be an increased risk for later developing AD. Here we treated young APP/PS1 AD model mice prophylactically with serotonin-sele...

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Detalles Bibliográficos
Autores principales: Ai, Peng-Hui, Chen, Si, Liu, Xian-Dong, Zhu, Xiao-Na, Pan, Yuan-Bo, Feng, Dong-Fu, Chen, Shengdi, Xu, Nan-Jie, Sun, Suya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216685/
https://www.ncbi.nlm.nih.gov/pubmed/32398165
http://dx.doi.org/10.1186/s40035-020-00194-2

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