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Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut

BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) i...

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Autor principal: El-Majzoub, Rania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216759/
https://www.ncbi.nlm.nih.gov/pubmed/32362651
http://dx.doi.org/10.12659/MSMBR.922414
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author El-Majzoub, Rania
author_facet El-Majzoub, Rania
author_sort El-Majzoub, Rania
collection PubMed
description BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) in children ages 7 months to 4 years living in Beirut. MATERIAL/METHODS: We collected and analyzed 120 urine specimens using the Shimadzu Atomic Absorption Spectrophotometer-6300 system equipped with an electrothermal atomization, and using a GFA-EX7i graphite furnace. RESULTS: The mean and standard deviation of Al level in urine revealed 8.978±12.275 μg/L, which is within the lower range of each of populations in Germany, Taiwan, and Poland. Vitamin intake, powder rice, and the use of Al utensils proved to be major determinants for Al level in urine (significant at 95%). CONCLUSIONS: The Shimadzu Atomic Absorption Spectrophotometer-6300 system proved again to be an optimal and reliable instrument that can be used for the determination of Al level in urine, especially if using a GFA-EX7i pyrolytic graphite furnace. High levels of Al were found in the urine of Lebanese children. However, the frequent consumption of canned food did not prove to be a significant factor in determining the Al level in urine.
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spelling pubmed-72167592020-05-18 Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut El-Majzoub, Rania Med Sci Monit Basic Res Laboratory Research BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) in children ages 7 months to 4 years living in Beirut. MATERIAL/METHODS: We collected and analyzed 120 urine specimens using the Shimadzu Atomic Absorption Spectrophotometer-6300 system equipped with an electrothermal atomization, and using a GFA-EX7i graphite furnace. RESULTS: The mean and standard deviation of Al level in urine revealed 8.978±12.275 μg/L, which is within the lower range of each of populations in Germany, Taiwan, and Poland. Vitamin intake, powder rice, and the use of Al utensils proved to be major determinants for Al level in urine (significant at 95%). CONCLUSIONS: The Shimadzu Atomic Absorption Spectrophotometer-6300 system proved again to be an optimal and reliable instrument that can be used for the determination of Al level in urine, especially if using a GFA-EX7i pyrolytic graphite furnace. High levels of Al were found in the urine of Lebanese children. However, the frequent consumption of canned food did not prove to be a significant factor in determining the Al level in urine. International Scientific Literature, Inc. 2020-05-04 /pmc/articles/PMC7216759/ /pubmed/32362651 http://dx.doi.org/10.12659/MSMBR.922414 Text en © Med Sci Monit, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Laboratory Research
El-Majzoub, Rania
Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title_full Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title_fullStr Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title_full_unstemmed Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title_short Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
title_sort biomonitoring of aluminum in urine of young lebanese children living in beirut
topic Laboratory Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216759/
https://www.ncbi.nlm.nih.gov/pubmed/32362651
http://dx.doi.org/10.12659/MSMBR.922414
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