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Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut
BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) i...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216759/ https://www.ncbi.nlm.nih.gov/pubmed/32362651 http://dx.doi.org/10.12659/MSMBR.922414 |
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author | El-Majzoub, Rania |
author_facet | El-Majzoub, Rania |
author_sort | El-Majzoub, Rania |
collection | PubMed |
description | BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) in children ages 7 months to 4 years living in Beirut. MATERIAL/METHODS: We collected and analyzed 120 urine specimens using the Shimadzu Atomic Absorption Spectrophotometer-6300 system equipped with an electrothermal atomization, and using a GFA-EX7i graphite furnace. RESULTS: The mean and standard deviation of Al level in urine revealed 8.978±12.275 μg/L, which is within the lower range of each of populations in Germany, Taiwan, and Poland. Vitamin intake, powder rice, and the use of Al utensils proved to be major determinants for Al level in urine (significant at 95%). CONCLUSIONS: The Shimadzu Atomic Absorption Spectrophotometer-6300 system proved again to be an optimal and reliable instrument that can be used for the determination of Al level in urine, especially if using a GFA-EX7i pyrolytic graphite furnace. High levels of Al were found in the urine of Lebanese children. However, the frequent consumption of canned food did not prove to be a significant factor in determining the Al level in urine. |
format | Online Article Text |
id | pubmed-7216759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72167592020-05-18 Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut El-Majzoub, Rania Med Sci Monit Basic Res Laboratory Research BACKGROUND: Aluminum (Al) is a ubiquitous, toxic metal to which infants and young toddlers are highly vulnerable. High Al exposure has been associated with various human pathologies. The aim of the present biomonitoring (BM) study was to provide a background for the levels of urinary aluminum (Al) in children ages 7 months to 4 years living in Beirut. MATERIAL/METHODS: We collected and analyzed 120 urine specimens using the Shimadzu Atomic Absorption Spectrophotometer-6300 system equipped with an electrothermal atomization, and using a GFA-EX7i graphite furnace. RESULTS: The mean and standard deviation of Al level in urine revealed 8.978±12.275 μg/L, which is within the lower range of each of populations in Germany, Taiwan, and Poland. Vitamin intake, powder rice, and the use of Al utensils proved to be major determinants for Al level in urine (significant at 95%). CONCLUSIONS: The Shimadzu Atomic Absorption Spectrophotometer-6300 system proved again to be an optimal and reliable instrument that can be used for the determination of Al level in urine, especially if using a GFA-EX7i pyrolytic graphite furnace. High levels of Al were found in the urine of Lebanese children. However, the frequent consumption of canned food did not prove to be a significant factor in determining the Al level in urine. International Scientific Literature, Inc. 2020-05-04 /pmc/articles/PMC7216759/ /pubmed/32362651 http://dx.doi.org/10.12659/MSMBR.922414 Text en © Med Sci Monit, 2020 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Laboratory Research El-Majzoub, Rania Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title | Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title_full | Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title_fullStr | Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title_full_unstemmed | Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title_short | Biomonitoring of Aluminum in Urine of Young Lebanese Children Living in Beirut |
title_sort | biomonitoring of aluminum in urine of young lebanese children living in beirut |
topic | Laboratory Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216759/ https://www.ncbi.nlm.nih.gov/pubmed/32362651 http://dx.doi.org/10.12659/MSMBR.922414 |
work_keys_str_mv | AT elmajzoubrania biomonitoringofaluminuminurineofyounglebanesechildrenlivinginbeirut |