Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever

We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterial...

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Autores principales: Fuller, Risa, Moshier, Erin, Jacobs, Samantha E, Tremblay, Douglas, Lancman, Guido, Coltoff, Alexander, Caro, Jessica, Mascarenhas, John, Rana, Meenakshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216765/
https://www.ncbi.nlm.nih.gov/pubmed/32420406
http://dx.doi.org/10.1093/ofid/ofaa138
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author Fuller, Risa
Moshier, Erin
Jacobs, Samantha E
Tremblay, Douglas
Lancman, Guido
Coltoff, Alexander
Caro, Jessica
Mascarenhas, John
Rana, Meenakshi
author_facet Fuller, Risa
Moshier, Erin
Jacobs, Samantha E
Tremblay, Douglas
Lancman, Guido
Coltoff, Alexander
Caro, Jessica
Mascarenhas, John
Rana, Meenakshi
author_sort Fuller, Risa
collection PubMed
description We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events.
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spelling pubmed-72167652020-05-15 Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever Fuller, Risa Moshier, Erin Jacobs, Samantha E Tremblay, Douglas Lancman, Guido Coltoff, Alexander Caro, Jessica Mascarenhas, John Rana, Meenakshi Open Forum Infect Dis Brief Report We compared risk of recurrent fever in patients with acute myeloid leukemia undergoing induction chemotherapy with febrile neutropenia without an infectious source in which antibacterials were de-escalated before neutrophil recovery versus continued. There was less recurrent fever when antibacterials were de-escalated early with no increased adverse events. Oxford University Press 2020-04-21 /pmc/articles/PMC7216765/ /pubmed/32420406 http://dx.doi.org/10.1093/ofid/ofaa138 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Fuller, Risa
Moshier, Erin
Jacobs, Samantha E
Tremblay, Douglas
Lancman, Guido
Coltoff, Alexander
Caro, Jessica
Mascarenhas, John
Rana, Meenakshi
Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title_full Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title_fullStr Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title_full_unstemmed Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title_short Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever
title_sort practicing antimicrobial stewardship: de-escalating antibiotics in patients with acute myeloid leukemia and neutropenic fever
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216765/
https://www.ncbi.nlm.nih.gov/pubmed/32420406
http://dx.doi.org/10.1093/ofid/ofaa138
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