Cargando…
Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV)
Traveller screening is being used to limit further global spread of 2019 novel coronavirus (nCoV) following its recent emergence. Here, we project the impact of different travel screening programs given remaining uncertainty around the values of key nCoV life history and epidemiological parameters....
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216848/ https://www.ncbi.nlm.nih.gov/pubmed/32511422 http://dx.doi.org/10.1101/2020.01.28.20019224 |
_version_ | 1783532493185482752 |
---|---|
author | Gostic, Katelyn M. Gomez, Ana C. R. Mummah, Riley O. Kucharski, Adam J. Lloyd-Smith, James O. |
author_facet | Gostic, Katelyn M. Gomez, Ana C. R. Mummah, Riley O. Kucharski, Adam J. Lloyd-Smith, James O. |
author_sort | Gostic, Katelyn M. |
collection | PubMed |
description | Traveller screening is being used to limit further global spread of 2019 novel coronavirus (nCoV) following its recent emergence. Here, we project the impact of different travel screening programs given remaining uncertainty around the values of key nCoV life history and epidemiological parameters. Even under best-case assumptions, we estimate that screening will miss more than half of infected travellers. Breaking down the factors leading to screening successes and failures, we find that most cases missed by screening are fundamentally undetectable, because they have not yet developed symptoms and are unaware they were exposed. These findings emphasize the need for measures to track travellers who become ill after being missed by a travel screening program. We make our model available for interactive use so stakeholders can explore scenarios of interest using the most up-to-date information. We hope these findings contribute to evidence-based policy to combat the spread of nCoV, and to prospective planning to mitigate future emerging pathogens. |
format | Online Article Text |
id | pubmed-7216848 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cold Spring Harbor Laboratory |
record_format | MEDLINE/PubMed |
spelling | pubmed-72168482020-06-07 Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) Gostic, Katelyn M. Gomez, Ana C. R. Mummah, Riley O. Kucharski, Adam J. Lloyd-Smith, James O. medRxiv Article Traveller screening is being used to limit further global spread of 2019 novel coronavirus (nCoV) following its recent emergence. Here, we project the impact of different travel screening programs given remaining uncertainty around the values of key nCoV life history and epidemiological parameters. Even under best-case assumptions, we estimate that screening will miss more than half of infected travellers. Breaking down the factors leading to screening successes and failures, we find that most cases missed by screening are fundamentally undetectable, because they have not yet developed symptoms and are unaware they were exposed. These findings emphasize the need for measures to track travellers who become ill after being missed by a travel screening program. We make our model available for interactive use so stakeholders can explore scenarios of interest using the most up-to-date information. We hope these findings contribute to evidence-based policy to combat the spread of nCoV, and to prospective planning to mitigate future emerging pathogens. Cold Spring Harbor Laboratory 2020-02-03 /pmc/articles/PMC7216848/ /pubmed/32511422 http://dx.doi.org/10.1101/2020.01.28.20019224 Text en http://creativecommons.org/licenses/by-nc/4.0/It is made available under a CC-BY-NC 4.0 International license (http://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Article Gostic, Katelyn M. Gomez, Ana C. R. Mummah, Riley O. Kucharski, Adam J. Lloyd-Smith, James O. Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title | Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title_full | Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title_fullStr | Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title_full_unstemmed | Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title_short | Estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-nCoV) |
title_sort | estimated effectiveness of traveller screening to prevent international spread of 2019 novel coronavirus (2019-ncov) |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216848/ https://www.ncbi.nlm.nih.gov/pubmed/32511422 http://dx.doi.org/10.1101/2020.01.28.20019224 |
work_keys_str_mv | AT gostickatelynm estimatedeffectivenessoftravellerscreeningtopreventinternationalspreadof2019novelcoronavirus2019ncov AT gomezanacr estimatedeffectivenessoftravellerscreeningtopreventinternationalspreadof2019novelcoronavirus2019ncov AT mummahrileyo estimatedeffectivenessoftravellerscreeningtopreventinternationalspreadof2019novelcoronavirus2019ncov AT kucharskiadamj estimatedeffectivenessoftravellerscreeningtopreventinternationalspreadof2019novelcoronavirus2019ncov AT lloydsmithjameso estimatedeffectivenessoftravellerscreeningtopreventinternationalspreadof2019novelcoronavirus2019ncov |