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Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion

Recent animal research suggests that it may soon be possible to support the human fetus in an artificial uterine environment for part of a pregnancy. A technique of extending gestation in this way (“ectogestation”) could be offered to parents of extremely premature infants (EPIs) to improve outcomes...

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Autores principales: Di Stefano, Lydia, Mills, Catherine, Watkins, Andrew, Wilkinson, Dominic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216952/
https://www.ncbi.nlm.nih.gov/pubmed/31697404
http://dx.doi.org/10.1111/bioe.12682
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author Di Stefano, Lydia
Mills, Catherine
Watkins, Andrew
Wilkinson, Dominic
author_facet Di Stefano, Lydia
Mills, Catherine
Watkins, Andrew
Wilkinson, Dominic
author_sort Di Stefano, Lydia
collection PubMed
description Recent animal research suggests that it may soon be possible to support the human fetus in an artificial uterine environment for part of a pregnancy. A technique of extending gestation in this way (“ectogestation”) could be offered to parents of extremely premature infants (EPIs) to improve outcomes for their child. The use of artificial uteruses for ectogestation could generate ethical questions because of the technology’s potential impact on the point of “viability”—loosely defined as the stage of pregnancy beyond which the fetus may survive external to the womb. Several medical decisions during the perinatal period are based on the gestation at which infants are considered viable, for example decisions about newborn resuscitation and abortion, and ectogestation has the potential to impact on these. Despite these possible implications, there is little existing evidence or analysis of how this technology would affect medical practice. In this paper, we combine empirical data with ethical analysis. We report a survey of 91 practicing Australian obstetricians and neonatologists; we aimed to assess their conceptual understanding of “viability,” and what ethical consequences they envisage arising from improved survival of EPIs. We also assess what the ethical implications of extending gestation should be for newborn and obstetric care. We analyze the concept of viability and argue that while ectogestation might have implications for the permissibility of neonatal life‐prolonging treatment at extremely early gestation, it should not necessarily have implications for abortion policy. We compare our ethical findings with the results of the survey.
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spelling pubmed-72169522020-05-13 Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion Di Stefano, Lydia Mills, Catherine Watkins, Andrew Wilkinson, Dominic Bioethics Special Issue: Ethics of Ectogenesis Recent animal research suggests that it may soon be possible to support the human fetus in an artificial uterine environment for part of a pregnancy. A technique of extending gestation in this way (“ectogestation”) could be offered to parents of extremely premature infants (EPIs) to improve outcomes for their child. The use of artificial uteruses for ectogestation could generate ethical questions because of the technology’s potential impact on the point of “viability”—loosely defined as the stage of pregnancy beyond which the fetus may survive external to the womb. Several medical decisions during the perinatal period are based on the gestation at which infants are considered viable, for example decisions about newborn resuscitation and abortion, and ectogestation has the potential to impact on these. Despite these possible implications, there is little existing evidence or analysis of how this technology would affect medical practice. In this paper, we combine empirical data with ethical analysis. We report a survey of 91 practicing Australian obstetricians and neonatologists; we aimed to assess their conceptual understanding of “viability,” and what ethical consequences they envisage arising from improved survival of EPIs. We also assess what the ethical implications of extending gestation should be for newborn and obstetric care. We analyze the concept of viability and argue that while ectogestation might have implications for the permissibility of neonatal life‐prolonging treatment at extremely early gestation, it should not necessarily have implications for abortion policy. We compare our ethical findings with the results of the survey. John Wiley and Sons Inc. 2019-11-07 2020-05 /pmc/articles/PMC7216952/ /pubmed/31697404 http://dx.doi.org/10.1111/bioe.12682 Text en © 2019 The Authors. Bioethics published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Issue: Ethics of Ectogenesis
Di Stefano, Lydia
Mills, Catherine
Watkins, Andrew
Wilkinson, Dominic
Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title_full Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title_fullStr Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title_full_unstemmed Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title_short Ectogestation ethics: The implications of artificially extending gestation for viability, newborn resuscitation and abortion
title_sort ectogestation ethics: the implications of artificially extending gestation for viability, newborn resuscitation and abortion
topic Special Issue: Ethics of Ectogenesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216952/
https://www.ncbi.nlm.nih.gov/pubmed/31697404
http://dx.doi.org/10.1111/bioe.12682
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