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IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art
Recent data support the theory of the involvement of IL‐17 in the pathogenesis of several chronic inflammatory skin diseases (psoriasis, atopic dermatitis, acne, hidradenitis suppurativa) and autoimmune skin diseases (alopecia areata, vitiligo, bullous diseases). Even if the role of IL‐17 in inflamm...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216999/ https://www.ncbi.nlm.nih.gov/pubmed/31663126 http://dx.doi.org/10.1111/ijd.14695 |
| _version_ | 1783532527124742144 |
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| author | Bernardini, Nicoletta Skroza, Nevena Tolino, Ersilia Mambrin, Alessandra Anzalone, Alessia Balduzzi, Veronica Colapietra, Daniela Marchesiello, Anna Michelini, Simone Proietti, Ilaria Potenza, Concetta |
| author_facet | Bernardini, Nicoletta Skroza, Nevena Tolino, Ersilia Mambrin, Alessandra Anzalone, Alessia Balduzzi, Veronica Colapietra, Daniela Marchesiello, Anna Michelini, Simone Proietti, Ilaria Potenza, Concetta |
| author_sort | Bernardini, Nicoletta |
| collection | PubMed |
| description | Recent data support the theory of the involvement of IL‐17 in the pathogenesis of several chronic inflammatory skin diseases (psoriasis, atopic dermatitis, acne, hidradenitis suppurativa) and autoimmune skin diseases (alopecia areata, vitiligo, bullous diseases). Even if the role of IL‐17 in inflammatory and autoimmune diseases has been reported extensively, its role in tumor is still controversial. Some reports show that Th17 cells eradicate tumors, while others reveal that they promote the initiation and early growth of tumors. Herein, we review the role of IL‐17 in the involvement of some common dermatologic diseases: psoriasis, atopic dermatitis, hidradenitis suppurativa, acne, vitiligo, melanoma, and nonmelanoma skin cancers. |
| format | Online Article Text |
| id | pubmed-7216999 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | John Wiley and Sons Inc. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-72169992020-05-13 IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art Bernardini, Nicoletta Skroza, Nevena Tolino, Ersilia Mambrin, Alessandra Anzalone, Alessia Balduzzi, Veronica Colapietra, Daniela Marchesiello, Anna Michelini, Simone Proietti, Ilaria Potenza, Concetta Int J Dermatol Review Recent data support the theory of the involvement of IL‐17 in the pathogenesis of several chronic inflammatory skin diseases (psoriasis, atopic dermatitis, acne, hidradenitis suppurativa) and autoimmune skin diseases (alopecia areata, vitiligo, bullous diseases). Even if the role of IL‐17 in inflammatory and autoimmune diseases has been reported extensively, its role in tumor is still controversial. Some reports show that Th17 cells eradicate tumors, while others reveal that they promote the initiation and early growth of tumors. Herein, we review the role of IL‐17 in the involvement of some common dermatologic diseases: psoriasis, atopic dermatitis, hidradenitis suppurativa, acne, vitiligo, melanoma, and nonmelanoma skin cancers. John Wiley and Sons Inc. 2019-10-30 2020-04 /pmc/articles/PMC7216999/ /pubmed/31663126 http://dx.doi.org/10.1111/ijd.14695 Text en © 2020 The Authors. International Journal of Dermatology published by Wiley Periodicals, Inc. on behalf of International Society of Dermatology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
| spellingShingle | Review Bernardini, Nicoletta Skroza, Nevena Tolino, Ersilia Mambrin, Alessandra Anzalone, Alessia Balduzzi, Veronica Colapietra, Daniela Marchesiello, Anna Michelini, Simone Proietti, Ilaria Potenza, Concetta IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title | IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title_full | IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title_fullStr | IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title_full_unstemmed | IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title_short | IL‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| title_sort | il‐17 and its role in inflammatory, autoimmune, and oncological skin diseases: state of art |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216999/ https://www.ncbi.nlm.nih.gov/pubmed/31663126 http://dx.doi.org/10.1111/ijd.14695 |
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