Cargando…

Addressing the risk domain in the long‐term management of pediatric asthma

There is growing concern regarding the long‐term outcomes of early and poorly controlled childhood asthma, either of which can potentially lead to the development of severe asthma in adults and irrecoverable loss of lung function leading to chronic obstructive pulmonary disease. These outcomes of in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamelmann, Eckard, von Mutius, Erika, Bush, Andrew, Szefler, Stanley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217022/
https://www.ncbi.nlm.nih.gov/pubmed/31732983
http://dx.doi.org/10.1111/pai.13175
_version_ 1783532532399079424
author Hamelmann, Eckard
von Mutius, Erika
Bush, Andrew
Szefler, Stanley J.
author_facet Hamelmann, Eckard
von Mutius, Erika
Bush, Andrew
Szefler, Stanley J.
author_sort Hamelmann, Eckard
collection PubMed
description There is growing concern regarding the long‐term outcomes of early and poorly controlled childhood asthma, either of which can potentially lead to the development of severe asthma in adults and irrecoverable loss of lung function leading to chronic obstructive pulmonary disease. These outcomes of inadequately controlled asthma should prompt a change in practice to better and/or earlier identify children at risk of adverse respiratory outcomes of asthma, to monitor disease progression, and to design intervention strategies that could either prevent or reverse asthma progression in children. The careful follow‐up of spirometry over time—in the form of lung function trajectories, the application of biomarkers to assist in the diagnosis of early asthma and medication selection for these patients, as well as methods to identify patients at risk of asthma attacks—can be used to develop individualized management strategies for children with asthma. It is now time for asthma specialists to communicate this information to patients, parents, and primary care physicians and to incorporate them into routine clinical assessments of children with asthma. In time, these concepts of risk management and prevention can be refined to provide a more comprehensive approach to asthma care so as to prevent adverse respiratory outcomes from poorly controlled childhood asthma.
format Online
Article
Text
id pubmed-7217022
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-72170222020-05-13 Addressing the risk domain in the long‐term management of pediatric asthma Hamelmann, Eckard von Mutius, Erika Bush, Andrew Szefler, Stanley J. Pediatr Allergy Immunol Review Article There is growing concern regarding the long‐term outcomes of early and poorly controlled childhood asthma, either of which can potentially lead to the development of severe asthma in adults and irrecoverable loss of lung function leading to chronic obstructive pulmonary disease. These outcomes of inadequately controlled asthma should prompt a change in practice to better and/or earlier identify children at risk of adverse respiratory outcomes of asthma, to monitor disease progression, and to design intervention strategies that could either prevent or reverse asthma progression in children. The careful follow‐up of spirometry over time—in the form of lung function trajectories, the application of biomarkers to assist in the diagnosis of early asthma and medication selection for these patients, as well as methods to identify patients at risk of asthma attacks—can be used to develop individualized management strategies for children with asthma. It is now time for asthma specialists to communicate this information to patients, parents, and primary care physicians and to incorporate them into routine clinical assessments of children with asthma. In time, these concepts of risk management and prevention can be refined to provide a more comprehensive approach to asthma care so as to prevent adverse respiratory outcomes from poorly controlled childhood asthma. John Wiley and Sons Inc. 2019-12-11 2020-04 /pmc/articles/PMC7217022/ /pubmed/31732983 http://dx.doi.org/10.1111/pai.13175 Text en © 2019 The Authors. Pediatric Allergy and Immunology published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Article
Hamelmann, Eckard
von Mutius, Erika
Bush, Andrew
Szefler, Stanley J.
Addressing the risk domain in the long‐term management of pediatric asthma
title Addressing the risk domain in the long‐term management of pediatric asthma
title_full Addressing the risk domain in the long‐term management of pediatric asthma
title_fullStr Addressing the risk domain in the long‐term management of pediatric asthma
title_full_unstemmed Addressing the risk domain in the long‐term management of pediatric asthma
title_short Addressing the risk domain in the long‐term management of pediatric asthma
title_sort addressing the risk domain in the long‐term management of pediatric asthma
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217022/
https://www.ncbi.nlm.nih.gov/pubmed/31732983
http://dx.doi.org/10.1111/pai.13175
work_keys_str_mv AT hamelmanneckard addressingtheriskdomaininthelongtermmanagementofpediatricasthma
AT vonmutiuserika addressingtheriskdomaininthelongtermmanagementofpediatricasthma
AT bushandrew addressingtheriskdomaininthelongtermmanagementofpediatricasthma
AT szeflerstanleyj addressingtheriskdomaininthelongtermmanagementofpediatricasthma