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TGFβ1 mimetic peptide modulates immune response to grass pollen allergens in mice

BACKGROUND: Transforming growth factor β1 (TGFβ1) is a cytokine that exerts immunosuppressive functions, as reflected by its ability to induce regulatory T (Treg) cell differentiation and inhibit Th1 and Th2 responses. Hence, peptides that mimic the active core domain of TGFβ1 may be promising candi...

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Detalles Bibliográficos
Autores principales: Araujo, Galber R., Aglas, Lorenz, Vaz, Emília R., Machado, Yoan, Huber, Sara, Himly, Martin, Duschl, Albert, Goulart, Luiz R., Ferreira, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217028/
https://www.ncbi.nlm.nih.gov/pubmed/31750952
http://dx.doi.org/10.1111/all.14108

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