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Sphingosine kinases protect murine embryonic stem cells from sphingosine‐induced cell cycle arrest

Sphingosine‐1‐phosphate (S1P) is a bioactive lipid molecule regulating organogenesis, angiogenesis, cell proliferation, and apoptosis. S1P is generated by sphingosine kinases (SPHK1 and SPHK2) through the phosphorylation of ceramide‐derived sphingosine. Phenotypes caused by manipulating S1P metaboli...

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Detalles Bibliográficos
Autores principales:	Pandey, Suveg, Banks, Kelly M., Kumar, Ritu, Kuo, Andrew, Wen, Duancheng, Hla, Timothy, Evans, Todd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217063/ https://www.ncbi.nlm.nih.gov/pubmed/31916656 http://dx.doi.org/10.1002/stem.3145

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