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Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

Age is a non-modifiable risk factor for the inflammation that underlies age-associated diseases; thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine profiling and bioinformatic analyses showed that Th17 cytokine production differentiates CD4(+) T cells from lean, normogly...

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Detalles Bibliográficos
Autores principales:	Bharath, Leena P., Agrawal, Madhur, McCambridge, Grace, Nicholas, Dequina A., Hasturk, Hatice, Liu, Jing, Jiang, Kai, Liu, Rui, Guo, Zhenheng, Deeney, Jude, Apovian, Caroline M., Snyder-Cappione, Jennifer, Hawk, Gregory S., Fleeman, Rebecca M., Pihl, Riley M.F., Thompson, Katherine, Belkina, Anna C., Cui, Licong, Proctor, Elizabeth A., Kern, Philip A., Nikolajczyk, Barbara S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217133/ https://www.ncbi.nlm.nih.gov/pubmed/32402267 http://dx.doi.org/10.1016/j.cmet.2020.04.015

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