A Cryptic Site of Vulnerability on the Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein

SARS-CoV-2 is a zoonotic virus that has caused a pandemic of severe respiratory disease—COVID-19—within several months of its initial identification. Comparable to the first SARS-CoV, this novel coronavirus’s surface Spike (S) glycoprotein mediates cell entry via the human ACE-2 receptor, and, thus,...

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Detalles Bibliográficos
Autores principales: Joyce, M. Gordon, Sankhala, Rajeshwer S., Chen, Wei-Hung, Choe, Misook, Bai, Hongjun, Hajduczki, Agnes, Yan, Lianying, Sterling, Spencer L., Peterson, Caroline E., Green, Ethan C., Smith, Clayton, de Val, Natalia, Amare, Mihret, Scott, Paul, Laing, Eric D., Broder, Christopher C., Rolland, Morgane, Michael, Nelson L., Modjarrad, Kayvon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217142/
https://www.ncbi.nlm.nih.gov/pubmed/32511298
http://dx.doi.org/10.1101/2020.03.15.992883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217142/
https://www.ncbi.nlm.nih.gov/pubmed/32511298
http://dx.doi.org/10.1101/2020.03.15.992883

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