Hippocampal long‐term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G‐protein‐gated inwardly rectifying potassium channel activity

Hippocampal synaptic plasticity disruption by amyloid‐β (Aβ) peptides + thought to be responsible for learning and memory impairments in Alzheimer's disease (AD) early stage. Failures in neuronal excitability maintenance seems to be an underlying mechanism. G‐protein‐gated inwardly rectifying p...

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Detalles Bibliográficos
Autores principales: Sánchez‐Rodríguez, Irene, Djebari, Souhail, Temprano‐Carazo, Sara, Vega‐Avelaira, David, Jiménez‐Herrera, Raquel, Iborra‐Lázaro, Guillermo, Yajeya, Javier, Jiménez‐Díaz, Lydia, Navarro‐López, Juan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217154/
https://www.ncbi.nlm.nih.gov/pubmed/31875959
http://dx.doi.org/10.1111/jnc.14946

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