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Integrative Modeling of a Sin3/HDAC Complex Sub-structure

Sin3/HDAC complexes function by deacetylating histones, condensing chromatin, and modulating gene expression. Although components used to build these complexes have been well defined, we still have only a limited understanding of the structure of the Sin3/HDAC subunits assembled around the scaffoldi...

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Detalles Bibliográficos
Autores principales: Banks, Charles A.S., Zhang, Ying, Miah, Sayem, Hao, Yan, Adams, Mark K., Wen, Zhihui, Thornton, Janet L., Florens, Laurence, Washburn, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217224/
https://www.ncbi.nlm.nih.gov/pubmed/32294434
http://dx.doi.org/10.1016/j.celrep.2020.03.080