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Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω‐Transaminases
Compared with biocatalysis in aqueous media, the use of enzymes in neat organic solvents enables increased solubility of hydrophobic substrates and can lead to more favorable thermodynamic equilibria, avoidance of possible hydrolytic side reactions and easier product recovery. ω‐Transaminases from A...
Autores principales: | Böhmer, Wesley, Volkov, Alexey, Engelmark Cassimjee, Karim, Mutti, Francesco G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217232/ https://www.ncbi.nlm.nih.gov/pubmed/32421034 http://dx.doi.org/10.1002/adsc.201901274 |
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