Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

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SARS-CoV-2 poses an immediate, major threat to public health across the globe. Here we report an in-depth molecular analysis to reconstruct the evolutionary origins of the enhanced pathogenicity of SARS-CoV-2 and other coronaviruses that are severe human pathogens. Using integrated comparative genom...

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Detalles Bibliográficos
Autores principales: Gussow, Ayal B., Auslander, Noam, Faure, Guilhem, Wolf, Yuri I., Zhang, Feng, Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217234/
https://www.ncbi.nlm.nih.gov/pubmed/32511301
http://dx.doi.org/10.1101/2020.04.05.026450
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