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DNAM1 and 2B4 Costimulatory Domains Enhance the Cytotoxicity of Anti-GPC3 Chimeric Antigen Receptor-Modified Natural Killer Cells Against Hepatocellular Cancer Cells in vitro

PURPOSE: Hepatocellular cancer (HCC) is the sixth most prevalent cancer and the third leading cause of cancer-related death worldwide. Cellular immunotherapy against glypican 3 (GPC3) has recently been used in the treatment of HCC, following the success of chimeric antigen receptor (CAR)-T therapy i...

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Detalles Bibliográficos
Autores principales:	Huang, Yao, Zeng, Jianxing, Liu, Teng, Xu, Qingyi, Song, Xianglin, Zeng, Jinhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217313/ https://www.ncbi.nlm.nih.gov/pubmed/32440221 http://dx.doi.org/10.2147/CMAR.S253565

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