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Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs

Methamphetamine use has increased over the past decade and the first use of methamphetamine is most often when women are of reproductive age. Methamphetamine accumulates in the liver; however, little is known about the effect of methamphetamine use on hepatic drug metabolism. Methamphetamine was adm...

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Detalles Bibliográficos
Autores principales: Soo, Jia Yin, Wiese, Michael D., Dyson, Rebecca M., Gray, Clint L., Clarkson, Andrew N., Morrison, Janna L., Berry, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217439/
https://www.ncbi.nlm.nih.gov/pubmed/32396581
http://dx.doi.org/10.1371/journal.pone.0233010