Thalamic, cortical, and amygdala involvement in the processing of a natural sound cue of danger

Animals use auditory cues generated by defensive responses of others to detect impending danger. Here we identify a neural circuit in rats involved in the detection of one such auditory cue, the cessation of movement-evoked sound resulting from freezing. This circuit comprises the dorsal subnucleus...

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Detalles Bibliográficos
Autores principales: Pereira, Ana G., Farias, Matheus, Moita, Marta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217448/
https://www.ncbi.nlm.nih.gov/pubmed/32396574
http://dx.doi.org/10.1371/journal.pbio.3000674
Descripción
Sumario:Animals use auditory cues generated by defensive responses of others to detect impending danger. Here we identify a neural circuit in rats involved in the detection of one such auditory cue, the cessation of movement-evoked sound resulting from freezing. This circuit comprises the dorsal subnucleus of the medial geniculate body (MGD) and downstream areas, the ventral area of the auditory cortex (VA), and the lateral amygdala (LA). This study suggests a role for the auditory offset pathway in processing a natural sound cue of threat.

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