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Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?

Genetic studies of both the human host and Mycobacterium tuberculosis (MTB) demonstrate independent association with tuberculosis (TB) risk. However, neither explains a large portion of disease risk or severity. Based on studies in other infectious diseases and animal models of TB, we hypothesized t...

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Detalles Bibliográficos
Autores principales:	McHenry, Michael L., Bartlett, Jacquelaine, Igo, Robert P., Wampande, Eddie M., Benchek, Penelope, Mayanja-Kizza, Harriet, Fluegge, Kyle, Hall, Noemi B., Gagneux, Sebastien, Tishkoff, Sarah A., Wejse, Christian, Sirugo, Giorgio, Boom, W. Henry, Joloba, Moses, Williams, Scott M., Stein, Catherine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217476/ https://www.ncbi.nlm.nih.gov/pubmed/32352966 http://dx.doi.org/10.1371/journal.pgen.1008728

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