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Murine gammaherpesvirus infection is skewed toward Igλ+ B cells expressing a specific heavy chain V-segment

One of the defining characteristics of the B cell receptor (BCR) is the extensive diversity in the repertoire of immunoglobulin genes that make up the BCR, resulting in broad range of specificity. Gammaherpesviruses are B lymphotropic viruses that establish life-long infection in B cells, and althou...

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Detalles Bibliográficos
Autores principales: Collins, Christopher M., Scharer, Christopher D., Murphy, Thomas J., Boss, Jeremy M., Speck, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217478/
https://www.ncbi.nlm.nih.gov/pubmed/32353066
http://dx.doi.org/10.1371/journal.ppat.1008438

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