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Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

Evolutionarily conserved circadian clocks generate 24-hour rhythms in physiology and behaviour that adapt organisms to their daily and seasonal environments. In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus is the principal co-ordinator of the cell-autonomous clocks distributed acro...

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Detalles Bibliográficos
Autores principales: Yang, Nan, Smyllie, Nicola J., Morris, Honor, Gonçalves, Cátia F., Dudek, Michal, Pathiranage, Dharshika R. J., Chesham, Johanna E., Adamson, Antony, Spiller, David G., Zindy, Egor, Bagnall, James, Humphreys, Neil, Hoyland, Judith, Loudon, Andrew S. I., Hastings, Michael H., Meng, Qing-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217492/
https://www.ncbi.nlm.nih.gov/pubmed/32352975
http://dx.doi.org/10.1371/journal.pgen.1008729

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