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Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator
Evolutionarily conserved circadian clocks generate 24-hour rhythms in physiology and behaviour that adapt organisms to their daily and seasonal environments. In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus is the principal co-ordinator of the cell-autonomous clocks distributed acro...
Autores principales: | Yang, Nan, Smyllie, Nicola J., Morris, Honor, Gonçalves, Cátia F., Dudek, Michal, Pathiranage, Dharshika R. J., Chesham, Johanna E., Adamson, Antony, Spiller, David G., Zindy, Egor, Bagnall, James, Humphreys, Neil, Hoyland, Judith, Loudon, Andrew S. I., Hastings, Michael H., Meng, Qing-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217492/ https://www.ncbi.nlm.nih.gov/pubmed/32352975 http://dx.doi.org/10.1371/journal.pgen.1008729 |
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