Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

Antimalarial drug resistance has historically arisen through convergent de novo mutations in Plasmodium falciparum parasite populations in Southeast Asia and South America. For the past decade in Southeast Asia, artemisinins, the core component of first-line antimalarial therapies, have experienced...

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Detalles Bibliográficos
Autores principales: Mathieu, Luana C, Cox, Horace, Early, Angela M, Mok, Sachel, Lazrek, Yassamine, Paquet, Jeanne-Celeste, Ade, Maria-Paz, Lucchi, Naomi W, Grant, Quacy, Udhayakumar, Venkatachalam, Alexandre, Jean SF, Demar, Magalie, Ringwald, Pascal, Neafsey, Daniel E, Fidock, David A, Musset, Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217694/
https://www.ncbi.nlm.nih.gov/pubmed/32394893
http://dx.doi.org/10.7554/eLife.51015

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