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Metabolites released from apoptotic cells act as novel tissue messengers

Caspase-dependent apoptosis accounts for ~90% of homeostatic cell turnover in the body(1), and regulates inflammation, cell proliferation, and tissue regeneration(2–4). How apoptotic cells mediate such diverse effects is not fully understood. Here, we profiled the apoptotic ‘metabolite secretome’ an...

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Detalles Bibliográficos
Autores principales: Medina, Christopher B., Mehrotra, Parul, Arandjelovic, Sanja, Perry, Justin S.A., Guo, Yizhan, Morioka, Sho, Barron, Brady, Walk, Scott F., Ghesquière, Bart, Krupnick, Alexander S., Lorenz, Ulrike, Ravichandran, Kodi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217709/
https://www.ncbi.nlm.nih.gov/pubmed/32238926
http://dx.doi.org/10.1038/s41586-020-2121-3