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Metabolites released from apoptotic cells act as novel tissue messengers
Caspase-dependent apoptosis accounts for ~90% of homeostatic cell turnover in the body(1), and regulates inflammation, cell proliferation, and tissue regeneration(2–4). How apoptotic cells mediate such diverse effects is not fully understood. Here, we profiled the apoptotic ‘metabolite secretome’ an...
Autores principales: | Medina, Christopher B., Mehrotra, Parul, Arandjelovic, Sanja, Perry, Justin S.A., Guo, Yizhan, Morioka, Sho, Barron, Brady, Walk, Scott F., Ghesquière, Bart, Krupnick, Alexander S., Lorenz, Ulrike, Ravichandran, Kodi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217709/ https://www.ncbi.nlm.nih.gov/pubmed/32238926 http://dx.doi.org/10.1038/s41586-020-2121-3 |
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