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Mitochondrial DNA alterations may influence the cisplatin responsiveness of oral squamous cell carcinoma

Cisplatin is the first-line chemotherapeutic agent for the treatment of oral squamous cell carcinoma (OSCC). However, the intrinsic or acquired resistance against cisplatin remains a major obstacle to treatment efficacy in OSCC. Recently, mitochondrial DNA (mtDNA) alterations have been reported in a...

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Detalles Bibliográficos
Autores principales:	Aminuddin, Amnani, Ng, Pei Yuen, Leong, Chee-Onn, Chua, Eng Wee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217862/ https://www.ncbi.nlm.nih.gov/pubmed/32398775 http://dx.doi.org/10.1038/s41598-020-64664-3

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