Insulin-like growth factor 1-induced enolase 2 deacetylation by HDAC3 promotes metastasis of pancreatic cancer

Enolase 2 (ENO2) is a key glycolytic enzyme in the metabolic process of glycolysis, but its potential function in pancreatic ductal adenocarcinoma (PDAC) is unclear. In this study, we observed a significant overexpression of ENO2 in PDAC tissues, and its expression was correlated with metastasis and...

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Detalles Bibliográficos
Autores principales: Zheng, Yan, Wu, Chao, Yang, Jimeng, Zhao, Yue, Jia, Huliang, Xue, Min, Xu, Da, Yang, Feng, Fu, Deliang, Wang, Chaoqun, Hu, Beiyuan, Zhang, Ze, Li, Tianen, Yan, Shican, Wang, Xuan, Nelson, Peter J., Bruns, Christiane, Qin, Lunxiu, Dong, Qiongzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217878/
https://www.ncbi.nlm.nih.gov/pubmed/32398667
http://dx.doi.org/10.1038/s41392-020-0146-6

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