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Arid1b haploinsufficiency in parvalbumin- or somatostatin-expressing interneurons leads to distinct ASD-like and ID-like behavior
Inhibitory interneurons are essential for proper brain development and function. Dysfunction of interneurons is implicated in several neurodevelopmental disorders, including autism spectrum disorder (ASD) and intellectual disability (ID). We have previously shown that Arid1b haploinsufficiency inter...
Autores principales: | Smith, Amanda L., Jung, Eui-Man, Jeon, Byeong Tak, Kim, Woo-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217886/ https://www.ncbi.nlm.nih.gov/pubmed/32398858 http://dx.doi.org/10.1038/s41598-020-64066-5 |
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