Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties

Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if exceptional polymer length of vHMM-HA is important for longevity. Here, we show that vHMM-HA (>6.1 MDa) has superior cytoprotecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Takasugi, Masaki, Firsanov, Denis, Tombline, Gregory, Ning, Hanbing, Ablaeva, Julia, Seluanov, Andrei, Gorbunova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217962/
https://www.ncbi.nlm.nih.gov/pubmed/32398747
http://dx.doi.org/10.1038/s41467-020-16050-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217962/
https://www.ncbi.nlm.nih.gov/pubmed/32398747
http://dx.doi.org/10.1038/s41467-020-16050-w

Ejemplares similares