Cargando…
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
Naked mole-rat (NMR), the longest-living rodent, produces very-high-molecular-mass hyaluronan (vHMM-HA), compared to other mammalian species. However, it is unclear if exceptional polymer length of vHMM-HA is important for longevity. Here, we show that vHMM-HA (>6.1 MDa) has superior cytoprotecti...
Autores principales: | Takasugi, Masaki, Firsanov, Denis, Tombline, Gregory, Ning, Hanbing, Ablaeva, Julia, Seluanov, Andrei, Gorbunova, Vera |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217962/ https://www.ncbi.nlm.nih.gov/pubmed/32398747 http://dx.doi.org/10.1038/s41467-020-16050-w |
Ejemplares similares
-
High molecular weight hyaluronan mediates the cancer resistance of the naked mole-rat
por: Tian, Xiao, et al.
Publicado: (2013) -
Naked mole‐rats are extremely resistant to post‐traumatic osteoarthritis
por: Taguchi, Taketo, et al.
Publicado: (2020) -
Hyaluronan goes to great length
por: Gorbunova, Vera, et al.
Publicado: (2020) -
Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming
por: Tan, Li, et al.
Publicado: (2017) -
DNA methylation clocks tick in naked mole rats but queens age more slowly than nonbreeders
por: Horvath, Steve, et al.
Publicado: (2022)