Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior

Newly born neurons express high levels of TUBA1A α-tubulin to assemble microtubules for neurite extension and to provide tracks for intracellular transport. In the adult brain, Tuba1a expression decreases dramatically. A mouse that harbors a loss-of-function mutation in the gene encoding TUBA1A (Tub...

Descripción completa

Detalles Bibliográficos
Autores principales: Buscaglia, Georgia, Northington, Kyle R., Moore, Jeffrey K., Bates, Emily Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2020
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218002/
https://www.ncbi.nlm.nih.gov/pubmed/32184299
http://dx.doi.org/10.1523/ENEURO.0045-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218002/
https://www.ncbi.nlm.nih.gov/pubmed/32184299
http://dx.doi.org/10.1523/ENEURO.0045-20.2020

Ejemplares similares