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Reduced TUBA1A Tubulin Causes Defects in Trafficking and Impaired Adult Motor Behavior

Newly born neurons express high levels of TUBA1A α-tubulin to assemble microtubules for neurite extension and to provide tracks for intracellular transport. In the adult brain, Tuba1a expression decreases dramatically. A mouse that harbors a loss-of-function mutation in the gene encoding TUBA1A (Tub...

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Detalles Bibliográficos
Autores principales:	Buscaglia, Georgia, Northington, Kyle R., Moore, Jeffrey K., Bates, Emily Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2020
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218002/ https://www.ncbi.nlm.nih.gov/pubmed/32184299 http://dx.doi.org/10.1523/ENEURO.0045-20.2020

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