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Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of Neural Network Activity through Non-Canonical p53 and Akt Signaling

Group 1 metabotropic glutamate receptors (Gp1 mGluRs), including mGluR1 and mGluR5, are critical regulators for neuronal and synaptic plasticity. Dysregulated Gp1 mGluR signaling is observed with various neurologic disorders, including Alzheimer’s disease, Parkinson’s disease, epilepsy, and autism s...

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Detalles Bibliográficos
Autores principales:	Liu, Dai-Chi, Soriano, Stephanie, Yook, Yeeun, Lizarazo, Simon, Eagleman, Daphne E., Tsai, Nien-Pei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2020
Materias:	Research Article: New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218008/ https://www.ncbi.nlm.nih.gov/pubmed/32161037 http://dx.doi.org/10.1523/ENEURO.0438-19.2020

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