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Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture
BACKGROUND: To test the hypothesis that optic nerve sheath diameter (ONSD) correlates with real-time changes in intracranial pressure, we performed ultrasound measurements of the ONSD in ambulatory patients undergoing elective lumbar puncture (LP). We conducted a prospective cohort study, including...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Milan
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218034/ https://www.ncbi.nlm.nih.gov/pubmed/32399786 http://dx.doi.org/10.1186/s13089-020-00173-8 |
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author | Schott, Christopher K. Hirzallah, Mohammad I. Heyman, Rock Lesky, Daniel N. Brant, Emily B. Callaway, Clifton W. |
author_facet | Schott, Christopher K. Hirzallah, Mohammad I. Heyman, Rock Lesky, Daniel N. Brant, Emily B. Callaway, Clifton W. |
author_sort | Schott, Christopher K. |
collection | PubMed |
description | BACKGROUND: To test the hypothesis that optic nerve sheath diameter (ONSD) correlates with real-time changes in intracranial pressure, we performed ultrasound measurements of the ONSD in ambulatory patients undergoing elective lumbar puncture (LP). We conducted a prospective cohort study, including adult patients undergoing LP in a non-emergent setting. We measured ONSD perpendicular to the optic nerve at 3 mm behind the globe in both eyes in the traverse and sagittal planes, with the patient supine. The primary outcome was change in ONSD from pre-LP to post-LP. We calculated association of opening and closing LP pressures with changes in the pre- and post-LP ONSD measurements. RESULTS: The mean patient age was 49.0 years (SD = 37–61, range 19–67) with 21 females (72.4%) and 26 (89.7%) white American (not Hispanic or Latino). The average opening pressure and closing pressures were 20.4 cm and 13.5 cm with a difference of 6.9 cm, (95% CI 3.9–10.0 cm). Pressures between the participants with baseline ONSD measurement > 5 mm (average opening pressure = 21.3 cm) to those < 5 mm (20.2 cm) differed by 1.1 cm (95% CI − 5.7 to 8.0). Linear regression revealed no association between the sagittal, transverse, average, and change in ONSD measurements with the observed LP opening pressure, change in LP pressure, or volume of cerebral spinal fluid (CSF) drained. CONCLUSIONS: In this study of ambulatory patients undergoing rapid decreases in ICP via elective LP, we detected no acute changes in ultrasonographic measurement of the ONSD. |
format | Online Article Text |
id | pubmed-7218034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Milan |
record_format | MEDLINE/PubMed |
spelling | pubmed-72180342020-05-15 Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture Schott, Christopher K. Hirzallah, Mohammad I. Heyman, Rock Lesky, Daniel N. Brant, Emily B. Callaway, Clifton W. Ultrasound J Original Article BACKGROUND: To test the hypothesis that optic nerve sheath diameter (ONSD) correlates with real-time changes in intracranial pressure, we performed ultrasound measurements of the ONSD in ambulatory patients undergoing elective lumbar puncture (LP). We conducted a prospective cohort study, including adult patients undergoing LP in a non-emergent setting. We measured ONSD perpendicular to the optic nerve at 3 mm behind the globe in both eyes in the traverse and sagittal planes, with the patient supine. The primary outcome was change in ONSD from pre-LP to post-LP. We calculated association of opening and closing LP pressures with changes in the pre- and post-LP ONSD measurements. RESULTS: The mean patient age was 49.0 years (SD = 37–61, range 19–67) with 21 females (72.4%) and 26 (89.7%) white American (not Hispanic or Latino). The average opening pressure and closing pressures were 20.4 cm and 13.5 cm with a difference of 6.9 cm, (95% CI 3.9–10.0 cm). Pressures between the participants with baseline ONSD measurement > 5 mm (average opening pressure = 21.3 cm) to those < 5 mm (20.2 cm) differed by 1.1 cm (95% CI − 5.7 to 8.0). Linear regression revealed no association between the sagittal, transverse, average, and change in ONSD measurements with the observed LP opening pressure, change in LP pressure, or volume of cerebral spinal fluid (CSF) drained. CONCLUSIONS: In this study of ambulatory patients undergoing rapid decreases in ICP via elective LP, we detected no acute changes in ultrasonographic measurement of the ONSD. Springer Milan 2020-05-13 /pmc/articles/PMC7218034/ /pubmed/32399786 http://dx.doi.org/10.1186/s13089-020-00173-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Article Schott, Christopher K. Hirzallah, Mohammad I. Heyman, Rock Lesky, Daniel N. Brant, Emily B. Callaway, Clifton W. Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title | Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title_full | Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title_fullStr | Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title_full_unstemmed | Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title_short | Ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
title_sort | ultrasound measurement of optic nerve sheath diameter pre- and post-lumbar puncture |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218034/ https://www.ncbi.nlm.nih.gov/pubmed/32399786 http://dx.doi.org/10.1186/s13089-020-00173-8 |
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