Transcriptome Profiling Reveals Indoxyl Sulfate Should Be Culpable of Impaired T Cell Function in Chronic Kidney Disease

Introduction: Chronic inflammation and immune system dysfunction have been evaluated as major factors in the pathogenesis of chronic kidney disease (CKD), contributing to the high mortality rates observed in these populations. Uremic toxins seem to be the potential “missing link.” Indoxyl sulfate (I...

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Detalles Bibliográficos
Autores principales: Xiang, Fangfang, Cao, Xuesen, Shen, Bo, Chen, Xiaohong, Guo, Man, Ding, Xiaoqiang, Zou, Jianzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218060/
https://www.ncbi.nlm.nih.gov/pubmed/32435647
http://dx.doi.org/10.3389/fmed.2020.00178

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