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Myriocin Effect on Tvrm4 Retina, an Autosomal Dominant Pattern of Retinitis Pigmentosa

Tvrm4 mice, a model of autosomal dominant retinitis pigmentosa (RP), carry a mutation of Rhodopsin gene that can be activated by brief exposure to very intense light. Here, we test the possibility of an anatomical, metabolic, and functional recovery by delivering to degenerating Tvrm4 animals, Myrio...

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Detalles Bibliográficos
Autores principales: Piano, Ilaria, D’Antongiovanni, Vanessa, Novelli, Elena, Biagioni, Martina, Dei Cas, Michele, Paroni, Rita Clara, Ghidoni, Riccardo, Strettoi, Enrica, Gargini, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218082/
https://www.ncbi.nlm.nih.gov/pubmed/32435178
http://dx.doi.org/10.3389/fnins.2020.00372