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Myriocin Effect on Tvrm4 Retina, an Autosomal Dominant Pattern of Retinitis Pigmentosa
Tvrm4 mice, a model of autosomal dominant retinitis pigmentosa (RP), carry a mutation of Rhodopsin gene that can be activated by brief exposure to very intense light. Here, we test the possibility of an anatomical, metabolic, and functional recovery by delivering to degenerating Tvrm4 animals, Myrio...
Autores principales: | Piano, Ilaria, D’Antongiovanni, Vanessa, Novelli, Elena, Biagioni, Martina, Dei Cas, Michele, Paroni, Rita Clara, Ghidoni, Riccardo, Strettoi, Enrica, Gargini, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218082/ https://www.ncbi.nlm.nih.gov/pubmed/32435178 http://dx.doi.org/10.3389/fnins.2020.00372 |
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