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Hyperglycemia contributes to the development of Leydig cell hyperplasia in male Spontaneously Diabetic Torii rats

Spontaneously Diabetic Torii (SDT) rats are a well-known animal model of non-obese type 2 diabetes mellitus. Although this animal model has been studied extensively over the last decade, the incidence rates of Leydig cell hyperplasia and tumors in this model have not been reported. In this study, pa...

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Detalles Bibliográficos
Autores principales: Nakane, Yoshitomi, Kemmochi, Yusuke, Ogawa, Naoto, Sasase, Tomohiko, Ohta, Takeshi, Higami, Yoshikazu, Fukai, Fumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218238/
https://www.ncbi.nlm.nih.gov/pubmed/32425345
http://dx.doi.org/10.1293/tox.2019-0088