Cargando…

Hyperglycemia contributes to the development of Leydig cell hyperplasia in male Spontaneously Diabetic Torii rats

Spontaneously Diabetic Torii (SDT) rats are a well-known animal model of non-obese type 2 diabetes mellitus. Although this animal model has been studied extensively over the last decade, the incidence rates of Leydig cell hyperplasia and tumors in this model have not been reported. In this study, pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nakane, Yoshitomi, Kemmochi, Yusuke, Ogawa, Naoto, Sasase, Tomohiko, Ohta, Takeshi, Higami, Yoshikazu, Fukai, Fumio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218238/ https://www.ncbi.nlm.nih.gov/pubmed/32425345 http://dx.doi.org/10.1293/tox.2019-0088

Ejemplares similares

Metabolic Disorders and Diabetic Complications in Spontaneously Diabetic Torii Lepr (fa) Rat: A New Obese Type 2 Diabetic Model
por: Kemmochi, Yusuke, et al.
Publicado: (2013)

Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats)
por: Kemmochi, Yusuke, et al.
Publicado: (2014)

Pathophysiological Characteristics of Diabetic Ocular Complications in Spontaneously Diabetic Torii Rat
por: Sasase, Tomohiko
Publicado: (2010)

Pathological Features of Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats
por: Tanaka, Yoshiaki, et al.
Publicado: (2019)

The Spontaneously Diabetic Torii Rat: An Animal Model of Nonobese Type 2 Diabetes with Severe Diabetic Complications
por: Sasase, Tomohiko, et al.
Publicado: (2013)

Gender Differences in Metabolic Disorders and Related Diseases in Spontaneously Diabetic Torii-Lepr (fa) Rats
por: Ohta, Takeshi, et al.
Publicado: (2014)

Hepatocellular adenoma with severe fatty change in a male Spontaneously Diabetic Torii rat
por: Taniai-Riya, Eriko, et al.
Publicado: (2016)

Effect of Food Restriction on Adipose Tissue in Spontaneously Diabetic Torii Fatty Rats
por: Morinaga, Hisayo, et al.
Publicado: (2009)

Diabetic Cataract in Spontaneously Diabetic Torii Fatty Rats
por: Kikuchi, Kasumi, et al.
Publicado: (2020)

Effects of Unilateral Nephrectomy on Renal Function in Male Spontaneously Diabetic Torii Fatty Rats: A Novel Obese Type 2 Diabetic Model
por: Katsuda, Yoshiaki, et al.
Publicado: (2014)

Differences in the Effects of Pentobarbital Anesthetic and Combination of Medetomidine Hydrochloride, Midazolam, and Butorphanol Tartrate Anesthetic on Electroretinogram in Spontaneously Diabetic Torii Fatty Rats
por: Hasegawa, Tetsuya, et al.
Publicado: (2022)

Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor phlorizin
por: KATSUDA, Yoshiaki, et al.
Publicado: (2015)

Urothelial hyperplasia with calculi (papillomatosis) in the urinary bladder of a male spontaneous diabetic Torii rat
por: Maejima, Takanori, et al.
Publicado: (2019)

Bone morphological analyses in Spontaneously Diabetic Torii (SDT) fatty rats
por: OHTA, Takeshi, et al.
Publicado: (2015)

Pathophysiological features in the brains of female Spontaneously Diabetic Torii (SDT) fatty rats
por: MAEKAWA, Tatsuya, et al.
Publicado: (2022)

Effects on Glycemic Control in Impaired Wound Healing in Spontaneously Diabetic Torii (SDT) Fatty Rats
por: Katsuhiro, Miyajima, et al.
Publicado: (2018)

Diabetic Complications in Obese Type 2 Diabetic Rat Models
por: Katsuda, Yoshiaki, et al.
Publicado: (2014)

Pathophysiological abnormalities in the brains of Spontaneously Diabetic Torii-Lepr (fa) (SDT fatty) rats, a novel type 2 diabetic model
por: MAEKAWA, Tatsuya, et al.
Publicado: (2018)

JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diabetic Rats
por: Sakata, Shohei, et al.
Publicado: (2014)

Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion
por: Sakimura, Katsuya, et al.
Publicado: (2018)

TORII: access the digital research community
por: Fabbrichesi, Marco E, et al.
Publicado: (2002)

Establishment of an Animal Model of Bisphosphonate-Related Osteonecrosis of the Jaws in Spontaneously Diabetic Torii Rats
por: Takaoka, Kazuki, et al.
Publicado: (2015)

Investigation of pharmacological responses to anti-diabetic drugs in female Spontaneously Diabetic Torii (SDT) fatty rats, a new nonalcoholic steatohepatitis (NASH) model
por: TORINIWA, Yasufumi, et al.
Publicado: (2018)

A New Spontaneously Diabetic Non-obese Torii Rat Strain With Severe Ocular Complications
por: Shinohara, Masami, et al.
Publicado: (2000)

Glucose Intolerance and Hyperlipidemia Prior to Diabetes Onset in Female Spontaneously Diabetic Torii (SDT) Rats
por: Shinohara, Masami, et al.
Publicado: (2004)

Osteomeles schwerinae Extract Prevents Diabetes-Induced Renal Injury in Spontaneously Diabetic Torii Rats
por: Sohn, Eunjin, et al.
Publicado: (2018)

Torii, an Open Portal over Open Archives
por: Bertocco, S
Publicado: (2001)

Congenital lipoid adrenal hyperplasia: Immunohistochemical study of testosterone synthesis in Leydig cells
por: Matsuoka, Kanako, et al.
Publicado: (2020)

Aster koraiensis extract prevents diabetes-induced retinal vascular dysfunction in spontaneously diabetic Torii rats
por: Kim, Junghyun, et al.
Publicado: (2017)

Crocodile Oil Disrupts Mitochondrial Homeostasis and Exacerbates Diabetic Kidney Injury in Spontaneously Diabetic Torii Rats
por: Wai Linn, Thiri, et al.
Publicado: (2022)

Relationship between Urinary Liver-Type Fatty Acid-Binding Protein (L-FABP) and Sarcopenia in Spontaneously Diabetic Torii Fatty Rats
por: Tanabe, Jun, et al.
Publicado: (2020)

Modified Western blotting for insulin and other diabetes-associated peptide hormones
por: Okita, Naoyuki, et al.
Publicado: (2017)

Methylglyoxal-derived hydroimidazolone residue of plasma protein can behave as a predictor of prediabetes in Spontaneously Diabetic Torii rats
por: Chen, Si Jing, et al.
Publicado: (2015)

Glucagon-like peptide-1 receptor agonist, liraglutide, attenuated retinal thickening in spontaneously diabetic Torii fatty rats
por: Inoue, Kazuho, et al.
Publicado: (2022)

Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism
por: Pathmanathan, S., et al.
Publicado: (2022)

Varying Phenotypes of Leydig Cell Hyperplasia of the Ovary: Two Case Reports
por: Caulkins, Margaret, et al.
Publicado: (2023)

Ovarian Leydig Cell Hyperplasia: An Unusual Case of Virilization in a Postmenopausal Woman
por: Mehta, Jaya M., et al.
Publicado: (2014)

Bilateral testicular Leydig cell hyperplasia presented incidentally: A case report
por: Al-zubi, Mohammad, et al.
Publicado: (2021)

Effects of Long-Term Treatment with Ranirestat, a Potent Aldose Reductase Inhibitor, on Diabetic Cataract and Neuropathy in Spontaneously Diabetic Torii Rats
por: Ota, Ayumi, et al.
Publicado: (2013)

Diabetic Retinopathy in the Spontaneously Diabetic Torii Rat: Pathogenetic Mechanisms and Preventive Efficacy of Inhibiting the Urokinase-Type Plasminogen Activator Receptor System
por: Cammalleri, Maurizio, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rgrsvrll23df5th76h08lee1fr