Heterogeneous Drug Efficacy of an Antibody-Drug Conjugate Visualized Using Simultaneous Imaging of Its Delivery and Intracellular Damage in Living Tumor Tissues

Anticancer drug efficacy varies because the delivery of drugs within tumors and tumor responses are heterogeneous; however, these features are often more homogenous in vitro. This difference makes it difficult to accurately determine drug efficacy. Therefore, it is important to use living tumor tiss...

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Detalles Bibliográficos
Autores principales: Gonda, Kohsuke, Negishi, Hiroshi, Takano-Kasuya, Mayumi, Kitamura, Narufumi, Furusawa, Naoko, Nakano, Yasushi, Hamada, Yoh, Tokunaga, Masayuki, Higuchi, Hideo, Tada, Hiroshi, Ishida, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218300/
https://www.ncbi.nlm.nih.gov/pubmed/32403030
http://dx.doi.org/10.1016/j.tranon.2020.100764

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