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Dinutuximab Synergistically Enhances the Cytotoxicity of Natural Killer Cells to Retinoblastoma Through the Perforin-Granzyme B Pathway

PURPOSE: Conventional chemotherapy and enucleation usually fail to cure advanced retinoblastoma. We investigated the retinoblastoma immune microenvironment and the efficacy of the combination of dinutuximab and CD16-expressing NK-92MI (NK-92MI(hCD16-GFP)) cells on retinoblastoma cells in this study....

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Detalles Bibliográficos
Autores principales:	Wang, Huixue, Yang, Jie, Pan, Hui, Tai, Mei Chee, Maher, Mohamed H, Jia, Renbing, Ge, Shengfang, Lu, Linna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218403/ https://www.ncbi.nlm.nih.gov/pubmed/32440155 http://dx.doi.org/10.2147/OTT.S228532

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