Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

Genetic factors contribute to the development of autism spectrum disorder (ASD), and although non-protein-coding regions of the genome are being increasingly implicated in ASD, the functional consequences of these variants remain largely uncharacterized. Induced pluripotent stem cells (iPSCs) enable...

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Detalles Bibliográficos
Autores principales: Ross, P. Joel, Mok, Rebecca S. F., Smith, Brandon S., Rodrigues, Deivid C., Mufteev, Marat, Scherer, Stephen W., Ellis, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218542/
https://www.ncbi.nlm.nih.gov/pubmed/32398033
http://dx.doi.org/10.1186/s13229-020-00333-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218542/
https://www.ncbi.nlm.nih.gov/pubmed/32398033
http://dx.doi.org/10.1186/s13229-020-00333-6

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