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Modeling neuronal consequences of autism-associated gene regulatory variants with human induced pluripotent stem cells

Genetic factors contribute to the development of autism spectrum disorder (ASD), and although non-protein-coding regions of the genome are being increasingly implicated in ASD, the functional consequences of these variants remain largely uncharacterized. Induced pluripotent stem cells (iPSCs) enable...

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Detalles Bibliográficos
Autores principales:	Ross, P. Joel, Mok, Rebecca S. F., Smith, Brandon S., Rodrigues, Deivid C., Mufteev, Marat, Scherer, Stephen W., Ellis, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218542/ https://www.ncbi.nlm.nih.gov/pubmed/32398033 http://dx.doi.org/10.1186/s13229-020-00333-6

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