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An investigation of genetic polymorphisms in heparan sulfate proteoglycan core proteins and key modification enzymes in an Australian Caucasian multiple sclerosis population
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease affecting the central nervous system in young adults. Heparan sulfate proteoglycans (HSPGs) are ubiquitous to the cell surface and the extracellular matrix. HSPG biosynthesis is a complex process involving enzymatic attachment o...
Autores principales: | Okolicsanyi, Rachel K., Bluhm, Julia, Miller, Cassandra, Griffiths, Lyn R., Haupt, Larisa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218574/ https://www.ncbi.nlm.nih.gov/pubmed/32398079 http://dx.doi.org/10.1186/s40246-020-00264-6 |
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