CRNDE: an oncogenic long non-coding RNA in cancers

Colorectal neoplasia differentially expressed (CRNDE) is a long non-coding RNA which has been proved upregulated in various cancers. Meanwhile, CRNDE has been demonstrated to be involved in multiple biological processes of different cancers according to previous study. Moreover, recent studies sugge...

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Detalles Bibliográficos
Autores principales: Lu, Ya, Sha, Huanhuan, Sun, Xun, Zhang, Yuan, Wu, Yang, Zhang, Junying, Zhang, Hui, Wu, Jianzhong, Feng, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218640/
https://www.ncbi.nlm.nih.gov/pubmed/32435153
http://dx.doi.org/10.1186/s12935-020-01246-3
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author Lu, Ya
Sha, Huanhuan
Sun, Xun
Zhang, Yuan
Wu, Yang
Zhang, Junying
Zhang, Hui
Wu, Jianzhong
Feng, Jifeng
author_facet Lu, Ya
Sha, Huanhuan
Sun, Xun
Zhang, Yuan
Wu, Yang
Zhang, Junying
Zhang, Hui
Wu, Jianzhong
Feng, Jifeng
author_sort Lu, Ya
collection PubMed
description Colorectal neoplasia differentially expressed (CRNDE) is a long non-coding RNA which has been proved upregulated in various cancers. Meanwhile, CRNDE has been demonstrated to be involved in multiple biological processes of different cancers according to previous study. Moreover, recent studies suggested CRNDE might be a potential diagnostic biomarker and prognostic predictor due to its high sensitivity and specificity in cancer tissues and plasma. In this review, we summarize the biological function of CRNDE and the relevant mechanisms in cancers to establish a molecular basis for the clinical use of CRNDE in the future.
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spelling pubmed-72186402020-05-20 CRNDE: an oncogenic long non-coding RNA in cancers Lu, Ya Sha, Huanhuan Sun, Xun Zhang, Yuan Wu, Yang Zhang, Junying Zhang, Hui Wu, Jianzhong Feng, Jifeng Cancer Cell Int Review Colorectal neoplasia differentially expressed (CRNDE) is a long non-coding RNA which has been proved upregulated in various cancers. Meanwhile, CRNDE has been demonstrated to be involved in multiple biological processes of different cancers according to previous study. Moreover, recent studies suggested CRNDE might be a potential diagnostic biomarker and prognostic predictor due to its high sensitivity and specificity in cancer tissues and plasma. In this review, we summarize the biological function of CRNDE and the relevant mechanisms in cancers to establish a molecular basis for the clinical use of CRNDE in the future. BioMed Central 2020-05-12 /pmc/articles/PMC7218640/ /pubmed/32435153 http://dx.doi.org/10.1186/s12935-020-01246-3 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Lu, Ya
Sha, Huanhuan
Sun, Xun
Zhang, Yuan
Wu, Yang
Zhang, Junying
Zhang, Hui
Wu, Jianzhong
Feng, Jifeng
CRNDE: an oncogenic long non-coding RNA in cancers
title CRNDE: an oncogenic long non-coding RNA in cancers
title_full CRNDE: an oncogenic long non-coding RNA in cancers
title_fullStr CRNDE: an oncogenic long non-coding RNA in cancers
title_full_unstemmed CRNDE: an oncogenic long non-coding RNA in cancers
title_short CRNDE: an oncogenic long non-coding RNA in cancers
title_sort crnde: an oncogenic long non-coding rna in cancers
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218640/
https://www.ncbi.nlm.nih.gov/pubmed/32435153
http://dx.doi.org/10.1186/s12935-020-01246-3
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