Neddylation inhibition activates the protective autophagy through NF-κB-catalase-ATF3 Axis in human esophageal cancer cells

BACKGROUND: Protein neddylation plays a tumor-promoting role in esophageal cancer. Our previous study demonstrated that neddylation inhibition induced the accumulation of ATF4 to promote apoptosis in esophageal cancer cells. However, it is completely unknown whether neddylation inhibition could indu...

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Detalles Bibliográficos
Autores principales: Liang, Yupei, Jiang, Yanyu, Jin, Xing, Chen, Ping, Heng, Yongqing, Cai, Lili, Zhang, Wenjuan, Li, Lihui, Jia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218644/
https://www.ncbi.nlm.nih.gov/pubmed/32398095
http://dx.doi.org/10.1186/s12964-020-00576-z

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