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HE4 overexpression decreases pancreatic cancer Capan-1 cell sensitivity to paclitaxel via cell cycle regulation

BACKGROUND: Paclitaxel is a first-line chemotherapy drug for pancreatic, ovarian, endometrial cancers and other malignancies. However, its efficacy is often compromised by decreased cell sensitivity or the development of resistance. Human epididymis protein 4 (HE4) is highly expressed in gynecologic...

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Detalles Bibliográficos
Autores principales:	Guo, Fengbiao, Li, Jinping, Qi, Yaozhi, Hou, Jianqing, Chen, Haibin, Jiang, Shi-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218645/ https://www.ncbi.nlm.nih.gov/pubmed/32435154 http://dx.doi.org/10.1186/s12935-020-01248-1

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