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Hypermethylation and decreased expression of TMEM240 are potential early-onset biomarkers for colorectal cancer detection, poor prognosis, and early recurrence prediction
BACKGROUND: Gene silencing by aberrant DNA methylation of promoter regions remains the most dominant phenomenon occurring during tumorigenesis. Improving the early diagnosis, prognosis, and recurrence prediction of colorectal cancer using noninvasive aberrant DNA methylation biomarkers has encouragi...
Autores principales: | Chang, Shih-Ching, Liew, Phui-Ly, Ansar, Muhamad, Lin, Shih-Yun, Wang, Sheng-Chao, Hung, Chin-Sheng, Chen, Jian-Yu, Jain, Shikha, Lin, Ruo-Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218647/ https://www.ncbi.nlm.nih.gov/pubmed/32398064 http://dx.doi.org/10.1186/s13148-020-00855-z |
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